This novel is a hybrid of science-fiction, fantasy, fable, folk tale, myth and horror. In 1959, a group of young woman meet at college and form a life long friendship. In 2000, they are reunited by a series of disturbing events. Carolyn, a retired lawyer, is called to defend an anti-social teenage girl from the death penalty after she abandoned her newborn baby. Ophy, a doctor, is called in to assist on a mysterious disease that is sweeping the world. Meanwhile the cruel Jake Jagger has been chosen by the shadowy Alliance as a man to watch. The Alliance is a organisation dedicated to reshaping society in its image but not even Jake is aware of the true motives of the Alliance's mysterious founder.
Carolyn and her friends learn of disturbing links between her court case, the disease and the Alliance. Now a group of middle aged women have to gather together to defeat the forces of darkness. This is a compulsively readable tale.